Does Stress effect elevated Bun and Creatnine?

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I brought my Fathers 11 year old Maine Coon into our home after my Fathers passing about a year ago.  He is a welcome addition to our family of 2 Labs and 1 Orange kitty.

Last year I had his teeth cleaned and his pre-op showed slightly elevated Bun and Creatnine counts, however Vet said his urine was concentrated so he thought he was O.K.

Last week took him in for his annual, they ran a senior panel and his Bun was 37 (high end of range is 34) and Creatnine was 2.7 (high end of range 2.3).  His urine is still concentrated (which Vet said was a good sign).  Maine Coone was adopted by my parents when he was one (found him in the back of their Dessert home).  He has always been very scared of strangers and the Vets.  

Vet is recommending a wet diet (he has been on dry food his entire life).  He is currently on Nature's Variety, I switched to the canned yesterday, doing well on it.  He has to go back in for more tests in 2 weeks to see if canned food has made a difference if counts are related to dehydration.

My question is can stress play into elevating those counts?  I will go back and have further tests, but just wanted more information from any of you in case those counts are still elevated.

Thank you!

Skeeter's Mom

I don't know about stress affecting BUN/creatinine, but it can affect other tests.

This is interesting.  It says dental disease may be linked to the development of CRF.  I've never read that before.  My 17-year-old cat had tooth extractions in the spring (he already had been diagnosed with CRF for a few years)

He had slightly elevated BUN and creatinine in the spring.  Switched him to all canned, and his BUN and creatinine levels reduced a little with one being in the normal range now.  He is on Wellness grain-free and Nature's Variety Instinct.  I don't know if they played a role or not.  He still drinks some water, but not as much as he did when he was on dry food.  But he is definitely better hydrated.  His fur softened.

I hope your cat's values improve.  Keeping fingers crossed.  Keep us posted.

A note about check-ups:  It might be a good idea to switch to checkups at least every 6 months since kitty is now over 10-years-old,particularly since kitty had the elevated BUN/creatinine levels.  I start doing 6 month exams on my cats and dogs once mine reach 7-years-old. 

It can be to a degree according to three different vets..

I do agree with Justme about the twice a yr... though after two animals in a row with chronic illness I take my 3 yr old girl in twice a yr too...

I don't think there is any solid documentation about stress affecting BUN and Creatinine, but stress can disrupt so many things that it would not surprise me at all.  Especially if your kitty does not tolerate going to vet very well.  However, I can tell you that I have a cat and she gets really stressed out going to the vet but that has not seemed to affect her BUN and Creatinine tests, since the last few have looked really good.  We have had several of these in the past year due to the recall.

Some vets believe that all older cats experience some degree of renal failure or renal insufficiency.  If your cat was on an all dry diet for most of his life, maybe that has something to do with the elevated levels along w/his age.  It will be interesting to see how he responds to the all wet diet.  Good luck, I hope it helps him out.

You might want to ask the vet if subcutaneous hydration (fluid therapy) might help.  I have a cat who is about 20 years old and she is experiencing test results very close to what you are seeing in your cat.  I give fluids at home twice a week and it really helps her.

Tissue dehydration can affect BUN and Creatinine levels.  Even though the urine is still concentrated, something as simple as dehydrated skin can cause a slight elevation.  Happens to me every time I get bloods in the winter.  Apparently, I don't drink enough in the winter.

Anyway, a sure fire way to see if the skin, the largest organ of the body, has enough hydration, is the pinch test.  For humans, pinch the skin on the back of the hands.  If it snaps right back, you are okay.  If it's a little slow, more hydration is necessary.  Same holds true for fur kids.  Pinch the fur and skin together on a fur kid and let go.  Should snap back quickly.

And JustMe, absolutely true about dental disease affecting kidneys in both animals and humans.  I have read many studies, for both species that say it is the case.  I have also seen first hand, being in the dental profession, what dental disease can do to all the other organs as well, including the heart.  It makes sense if you think about it.

The filthiest part of the body is the mouth.  Gingivitis is a proliferation of oral bacteria, which are then trapped below the gumline, unable to be accessed by toothbrush or mouthwash.  If allowed to accumulate to out of control proportions, the bcateria can easily enter the bloodstream and set up house in the next organ it finds.  One very interesting human study that I liked, recommended co-enzyme Q-10 at a dosage of 300 mg. 2x daily.  My husband had bad gingivitis and went 4 times a year for cleanings....scaling and root planing.  He wouldn't let me clean and scale......LOL.....I guess I frighten him with sharp instruments.  Afetr about a year of co-Q, he has improved so well, that as of his appointment last Thursday, his hygienist cut him back to 2 times a year.  She was very impressed with his progress.

Gizmo was on 60 mg of co-Q10 since the age of 5, when he was first diagnosed with hypertrophic cardiomyopathy.  At the age of 5 he had lost all of his upper and lower anterior teeth, which the vet said was no big deal, because those teeth are hardly used.  Big deal to me, based on profession ;).  Ejection fraction for Giz from echocardiogram, at age 5 was 78%, at age 10 it was 93%.  I'm sure it was the co-Q.

And as an aside, anyone taking a statin drug should be taking at least 300-600mg/day.  The pharmacists will usually tell you, but the MD's generally don't.


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